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Glabridin (Licorice Root Extract)

INCI: Glycyrrhiza Glabra Root Extract

Isoflavonoid from licorice root. Inhibits tyrosinase and suppresses inflammation. Main active in depigmenting products based on licorice extract.

BrighteningSoothing

Evidence by route

Topical application

C

Weak evidence. In vitro data, open-label studies, or expert consensus.

Clinical data are limited to small studies. Tyrosinase inhibition in vitro is significant. In melasma, moderate improvement has been shown, comparable to 4% hydroquinone in one small RCT.

  • Amer M et al. J Cosmet Dermatol. 2009;8(4):249-252.
  • Yokota T et al. Pigment Cell Res. 1998;11(6):355-361.

Tolerability and safety

Irritation potential

Low

Allergen risk

Low

Pregnancy

Caution

Skin types

Suitable for

SensitiveDryNormalCombinationOily

Frequently asked questions

Is Glabridin (Licorice Root Extract) safe during pregnancy?

Glabridin (Licorice Root Extract) should be used with caution during pregnancy. Consulting a dermatologist or OB-GYN is advisable.

What skin types is Glabridin (Licorice Root Extract) for?

Glabridin (Licorice Root Extract) suits: sensitive, dry, normal, combination, oily.