A ceramide-related lipid. It strengthens the barrier and holds water in the skin. Well tolerated.
Topical application
BLimited evidence. One RCT or several controlled studies with limitations.
A barrier lipid. Safe.
Glycosphingolipid is a lipid related to ceramides, made of a sphingoid base linked to a sugar. In cosmetics it is part of the lipid matrix that seals the skin barrier, helping to reduce water loss and keep the skin cohesive. On efficacy, it sits in a category with reasonable support. Barrier lipids, like ceramides and their relatives, help reinforce barrier function and retain moisture. It works as a barrier-supporting active, especially on dry or compromised skin, and more so when paired with ceramides and cholesterol. In topical use it has no systemic relevance, so it can be applied in pregnancy and breastfeeding. Irritation and allergy potential are low, so it suits sensitive and reactive skin. Most people tolerate it very well.
Irritation potential
LowAllergen risk
LowPregnancy
SafeSuitable for
The Evigrade extension adds an evidence panel to iHerb, Sephora, Druni and 12 more stores. This ingredient and every other one in the product show evidence-tier, allergen risk and pregnancy/lactation flags at a glance.
Glycosphingolipid is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
Glycosphingolipid suits: normal, dry, combination, oily, sensitive.
A ceramide-related lipid.
The INCI name is Glycosphingolipid. It may also appear as: Гликосфинголипид.
Published: · updated: