Glycosphingolipid
A ceramide-related lipid. It strengthens the barrier and holds water in the skin. Well tolerated.
Evidence by route
Topical application
A barrier lipid. Safe.
- CIR Cosmetic Ingredient Review safety assessment
How to read tiers A–F
- BLimited evidence. One RCT or several controlled studies with limitations
Tolerability and safety
- Irritation potential
- Low
- Allergen risk
- Low
- Pregnancy
- Safe
- Suitable for
- Normal, Dry, Combination, Oily, Sensitive
About this ingredient
Glycosphingolipid is a lipid related to ceramides, made of a sphingoid base linked to a sugar. In cosmetics it is part of the lipid matrix that seals the skin barrier, helping to reduce water loss and keep the skin cohesive. On efficacy, it sits in a category with reasonable support. Barrier lipids, like ceramides and their relatives, help reinforce barrier function and retain moisture. It works as a barrier-supporting active, especially on dry or compromised skin, and more so when paired with ceramides and cholesterol. In topical use it has no systemic relevance, so it can be applied in pregnancy and breastfeeding. Irritation and allergy potential are low, so it suits sensitive and reactive skin. Most people tolerate it very well.
Frequently asked questions
Is Glycosphingolipid safe during pregnancy?
Glycosphingolipid is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
What skin types is Glycosphingolipid for?
Glycosphingolipid suits: normal, dry, combination, oily, sensitive.
What is Glycosphingolipid and what does it do in cosmetics?
A ceramide-related lipid.
What's the INCI name for Glycosphingolipid?
The INCI name is Glycosphingolipid.
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