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Hydrolyzed Yeast Protein

Low-molecular-weight protein hydrolysate from yeast – a source of amino acids and peptides. Supports hydration and epidermal regeneration. Pregnancy-safe.

Evidence by route

B

Topical application

Peptide and amino-acid humectant. Moderate evidence (clinical data for hydration).

How to read tiers A–F
  • BLimited evidence. One RCT or several controlled studies with limitations

Tolerability and safety

Irritation potential
Low
Allergen risk
Low
Pregnancy
Safe
Suitable for
Normal, Dry, Combination, Oily, Sensitive

About this ingredient

Hydrolyzed yeast protein is the product of enzymatic hydrolysis of yeast proteins into short peptides and free amino acids. INCI: Hydrolyzed Yeast Protein. It contains glutamate, proline, alanine, serine and nucleotides. In cosmetics it works as a humectant and regenerative component. Low-mass peptides (<3 kDa) penetrate the stratum corneum, rebuild the NMF and support the barrier. Free amino acids serve as substrate for filaggrin synthesis. Clinical studies show improved skin hydration and elasticity. It is often used in creams for mature skin and post-procedure products. Use levels run from 1 to 5%. Stable in formulas with pH 4-7. Pregnancy safety. Skin absorption into the systemic circulation is minimal. Yeast hydrolysates are a food ingredient with unquestioned safety. Skin profile. Low irritation potential. Low allergen risk, with rare cases in people hypersensitive to yeast. Non-comedogenic. Suitable for all skin types. Active effect at level B – clinical data for hydration; collagen-stimulation data are weaker.

Frequently asked questions

Is Hydrolyzed Yeast Protein safe during pregnancy?

Hydrolyzed Yeast Protein is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.

What skin types is Hydrolyzed Yeast Protein for?

Hydrolyzed Yeast Protein suits: normal, dry, combination, oily, sensitive.

What is Hydrolyzed Yeast Protein and what does it do in cosmetics?

Low-molecular-weight protein hydrolysate from yeast – a source of amino acids and peptides.

Is Hydrolyzed Yeast Protein comedogenic?

On the Fulton scale 0/5 – non-comedogenic. For acne-prone skin, a rating of 3 or higher suggests choosing an alternative.

What's the INCI name for Hydrolyzed Yeast Protein?

The INCI name is Hydrolyzed Yeast Protein. It may also appear as: Hydrolyzed Yeast.

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